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Tumor Model mouse–based Autoantibody Discovery

  • Identification of Ag of antibodies specific to liver cancer
    • FASN (fatty acid synthase)
    • ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase)
    • SF3b1(Splicing Factor 3b Subunit 1)
    • EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A)
  • Screening with Page-Display
  • Confirmation and production of recombinant protein expression
  • Identification of recombinant antigen-auto antibody response through ELISA method