• mass spectrometry analysis, custom protein service
  • human chorionic gonadotropin, 2-d electrophoresis
  • ige immunoblotting, post-translational modification analysis
  • polyacrylamide gel electrophoresis, 2-d electrophoresis
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Proteomics Technology

post-translational modification analysis, ige immunoblotting

1, 2-Dimensional Electrophoresis

  • Sample preparation
  • Gel staining
  • Image analysis
  • Isoelectric Focusing
  • SDS-PAGE

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human chorionic gonadotropin, polyacrylamide gel electrophoresis

Mass Spectrometry Analysis

  • LC-MS/MS
  • MALDI-TOF
  • Peptide Mass fingerprinting
  • Protein Identification
  • Intact Mass Measurement
  • De novo peptide sequencing

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2-d electrophoresis, custom protein service

Post-Translational
Modification Analysis

  • Phosphorylation, Acetylation,
    Methylation etc
  • Enzymatic Deglycosylation
  • Glycan Analysis

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Custom Protein Services

  • Protein purification &
    Characterization
  • Western Blotting
  • Assay Development

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Why Proteomics?

A biomarker, or biological marker, is in general a substance used as an indicator of a biological state.
It is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. Biomarker discovery has been accelerated by proteomics, which study to entire protein expression at any given time in cell or tissue. If a certain protein is the functional molecule in cells, measurement of the differential expression of proteins could indicate disease-specific changes in tissues or organs.

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Mass spectrometry (MS) is an analytical technique that measures the molecular weight of molecules based upon the motion of a charged particle in an electric or magnetic field. It is used for determining masses of particles, for determining the elemental composition of a sample or molecule, and for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. This technique is performed by a mass spectrometer. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measuring their mass-to-charge ratios (m/z).

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